The teeth selected as influential teeth were submaxillary first bicuspid and third molar tooth, maxillary canine and second bicuspid, maxillary first bicuspid, first and second molar teeth. To be noted is the fact that “―” signal in the model equation indicates the following general trend such as teeth elevating blood pressure but maxillary second bicuspid and second molar tooth lowering blood pressure. These interesting findings led us to recognize the key notion “Teeth are our organs”; however, details shall be described later. It is noteworthy that the third molar tooth (wisdom tooth) is deeply involved in elevation of blood pressure. According to the common sense in the dental field, the wisdom tooth is useless but on the contrary, it seems to us that this tooth might play an important role in maintaining vitality and vigor of humans. In hypertensive patients, there is a possibility that continuous and too strong stimulation is given to the teeth conducive to increasing blood pressure such as the wisdom tooth, maxillary first bicuspid, first molar and canine as well as submaxillary first bicuspid and second bicuspid, or weaker stimulation is given to maxillary second molar and second bicuspid which lower blood pressure. In hypotensive patients, we can anticipate that hypotension is induced by the contrary mechanism related to the above-stated teeth. This is a key theme related to the organic features of teeth, and accordingly, this shall be referred to below in details. This would appear likely to imply extremely important issues.
Figures 27 and 28 show the equation model regarding the maximum and the minimum blood pressures in the cases with less than 15 teeth.
In terms of the minimum blood pressure, we obtained 0.9 as the multiple correlation coefficient, 0.81 as the contribution ratio and 0.0002 as the risk ratio P, all of which suggests extremely high reliability, indicating that teeth play an important role in the diastolic blood pressure. The selected teeth were maxillary medial incisor and submaxillary canine tooth. These teeth seem contributory to decrease of blood pressure.
As briefed above, the order of teeth to be lost is maxillary and submaxillary molar, bicuspid, maxillary canine and front teeth, and finally submaxillary canine and front teeth, in this loosing order. This means that the subjects with less than 15 teeth hardly have molar teeth. In the equation model concerning the maximum blood pressure, the contributory ratio indicative of power of explanation is 0.42; this means that if the complete explanation by this model is regarded as 100, only 42% can be explained. This indicates that in addition to the stipulated explanatory variables, there might exist more influential other factors. In any events, when the remaining teeth become less in number, the influential power of teeth on the maximum blood pressure is negligible. This phenomenon is attributed to absence of the teeth influential to the blood pressure due to extraction.
The results obtained by the above-stated multi-variable analysis verified that teeth provide influences on the blood pressure without any influences of the systemic background factors and furthermore, the influences of teeth are so decisive to control the blood pressure in comparison with other systemic factors. This is an epoch-making discovery because the total population under treatment of hypertension is estimated to amount to more than 10 million in Japan. If candidates with border-line hypertension and latent hypertension are included, more than 2 to 3-fold population, namely approximately 30 % of Japanese people are suffering from hypertension. As is well known, hypertension is classified into secondary hypertension of which causes are clarified and essential hypertension characteristic of unknown causes whereas more than 90 % of the patients belongs to the latter essential hypertension. Despite of remarkable progress of medical researches, actual causes of this important disease from which more than 30 million people are suffering have not yet been clarified, suggesting that there might be unexcavated blind points as the research fields. I am now confident that teeth would be responsible for this disease. Shall we review individual testimony from patients which surely convince us of our above-stated confidence?
I was suffering from hypertension for about 10 years. In April 1993, plates were implanted at Muratsu Clinic to correct irregular bites. As the results, the diastolic blood pressure was lowered to 80s mmHg, with the systolic blood pressure decreasing to 130s mmHg. Subsequently, my blood pressures have been continuously stable. (64 years old, male, Fukuoka)
This patient had received treatment of hypertension in the Kyushu University Detached Hospital. Judging from his age, it was very rare to have his own teeth under a relatively complete condition. As shown in his memo, he was diagnosed to have hypertension about 10 years ago and he took the prescribed anti-hypertensive agents; however, his hypertension was not improved, resulting in continuously persisting. However, immediately after treatment of abnormal occlusion, efficacy was promptly observed to show blood pressure decrease down to the normal healthy levels (Figure 29). You can find sudden decrease of blood pressure immediately after commencement of occlusion treatment from this figure.
This fact corroborates that teeth are responsible for onset of persisting hypertension. These data had been independently stored as the record of his blood pressures in a hospital where he received medications; however, he kindly brought these data to us because he was so pleased of improvement of hypertension by our dental treatment. Before and after out dental treatment, no alterations of prescribed drugs including combined use with other drugs were made. He is still continuing his preventive cares at our KOS clinic but no relapse of hypertension is observed.
Next witness comes from a female patient who showed improvement of hypotension and systemic health conditions following recovery of dental health. Coupled with testimony of her son, this letter surely makes you recognize the fact that teeth provide influences not only blood pressure, autonomic nerve but also systemic conditions.
Since my childhood, I was always suffering from some diseases. When I
was 19 years old, I suffered from Basedow's disease and I felt some anxiety;
furthermore, I was so nervous about health and whenever tiny abnormality was
perceived, I became depressed. Under such conditions, I got married and
gave birth to a child. Although I was susceptible to diseases, I kept
working very hard. Under such situations, I was introduced by my
elder brother to Dr. Muratsu and I received the dental treatment and gradually,
I recognized that my health was recovered. Very tiny improvements occurred
including stepping up high stairways, easily walking in a bustled area and
disappearance of stiff shoulder and eye ball pains.
Significant changes were found in blood pressures. Before treatments,
I was suffering from hypotension with the systolic blood pressure of 87 mmHg and
as the maximum up to 95 mmHg even during pregnancy. I was not so nervous
about lowered blood pressures because I had been accustomed to hypotension but
after completion of the dental treatment, I happened to know elevation of the
systolic blood pressure to 110～120 mmHg. I could not find out any other
causes except treatment of teeth. I was surprised at this change because I
had considered that hypotension could not be cured.
My son also received treatment of rhinitis. He always sniffled but
immediately after dental treatment, he appeared without any sniffling from Dr.
Muratsu’s office. He had had very nervous characters previously but
recently, this feature was improved. When he became a fourth grade
elementary school child, he entered an extracurricular club. Dr. Muratsu,
I really appreciate your kind treatment so that all of our family members are
confident about our health.
(41-year-old woman, Kumamoto)
This patient had a partial irregular occlusion in the front part which should be treated by means of prosthetic correction methods.
Figure 25
Equation model of systolic blood pressure (1)
(Current No. of teeth: ≧13 teeth)
------------------------------------------------------
Systolic blood pressure = 157
+13.1 X Submaxillary third molar
+16.3 X Maxillary first bicuspid
+5.1 X Maxillary first molar
－10.8 X Maxillary second molar
－0.44 X pulse rate－21.6 X Albumin/globulin ratio
+2.6 X Ca amount
------------------------------------------------------
Multiple correlation coefficient=0.8
Contribution ratio =0.65
P value＜0.0001
This is the equation model for systolic blood pressure (General linear multiple regression model) in the cases with more than 13 teeth as the current residual number of teeth. The multiple correlation coefficient indicating the degree of correlation was 0.8, with the contribution ratio indicative of power of explanation being 0.65, and the p value indicative of the statistical significance being 0.0001. All of them suggest that the scientific credibility is extremely high. The fact that the dental factors are selected as the explanatory variables on the right-hand side means that teeth are involved in systolic blood pressure. Particularly, maxillary first bicuspid, first molar, second molar and submaxillary wisdom tooth seem to be implicated.
Figure 26
Equation model of diastolic blood pressure (1)
(Current No. of teeth: ≧13 teeth)
------------------------------------------------------
Diastolic blood pressure = 14.7
+7.96 X Submaxillary first bicuspid
+4.99 X Submaxillary third molar
+7.95 X Maxillary canine
－4.03 X Maxillary second bicuspid
+0.81 X Age
－0.01 X Noradrenaline level
+0.11 X HDL cholesterol level
(Medical items are obtained from the serum.)
------------------------------------------------------
Multiple correlation coefficient=0.89
Contribution ratio =0.79
P value＜0.0001
This is the equation model for systolic blood pressure in the cases with more than 13 teeth as the current residual number of teeth. The multiple correlation coefficient was 0.89, with the contribution ratio being 0.79, and the p value being as small as 0.0001. All of them suggest that the scientific credibility is extremely high. The fact that the dental factors are selected as the explanatory variables on the right-hand side means that teeth are involved in diastolic blood pressure. Particularly, maxillary canine, second bicuspid, submaxillary bicuspid and wisdom tooth seem to be deeply implicated.
Figure 27
Equation model of systolic blood pressure (2)
(0＜Current No. of teeth: ＜15 teeth)
------------------------------------------------------
Systolic blood pressure = －197
+25.2 X Total protein amount
－0.14 X Triglyceride level
+5.1 X Noradrenaline level
+0.003 X Na level
------------------------------------------------------
Multiple correlation coefficient=0.65
Contribution ratio =0.42
P value＜0.02
This is the equation model for systolic blood pressure in the cases with less than 15 teeth as the current residual number of teeth. Both the multiple correlation coefficients and the contribution ratio were low, with the p value being high. All of them suggest that this equation model is not credible. In addition, factors related to teeth are not included therein. It postulated that any other factors than the selected factors for this equation might be strongly involved.
Figure 28
Equation model of diastolic blood pressure (2)
(0＜Current No. of teeth: ＜15 teeth)
------------------------------------------------------
Diastolic blood pressure = －13.2
－4.77 X Maxillary medial incisor
－7.77 X Sub maxillary canine
+13.5 X Albumin level
+23.3 X Mg level
－1.45 X Ca level
+0.009 X Noradrenaline level
------------------------------------------------------
Multiple correlation coefficient=0.90
Contribution ratio =0.81
P value＜0.0002
This is the equation model for diastolic blood pressure in the cases with less than 15 teeth as the current residual number of teeth. The multiple correlation coefficient was 0.90, with the contribution ratio being 0.81, and the p value being as small as 0.0002. All of them suggest that the scientific credibility is extremely high. It seems that teeth are implicated. In particular, with less residual sub maxillary teeth, stronger influences of maxillary medial incisor and sub maxillary canine are observed.
Figure 29
An example in which treatment of abnormal occlusion alleviated hypertension
Previously, this patient had 152mmHg as the mean systolic blood pressure, 94 mmHg as the diastolic blood pressure, indicating persisting hypertensive situation. Immediately after commencement of occlusion treatment, blood pressures were reduced such as 130 mmHg as systolic blood pressure and 80 mmHg as diastolic blood pressure.
No comments:
Post a Comment